Folate and B12 are frequently selected as supplements for individuals striving for a healthy lifestyle. Folate, also referred to as Vitamin B9, is integral for cell growth and development within the body. It is particularly important for pregnant women, as it can aid in preventing birth defects in the newborn’s brain and spine. On the other hand, Vitamin B12 is responsible for the maintenance of healthy nerve cells, red blood cells, and DNA synthesis.
The combination of folate and B12 is essential for maintaining a healthy body, and supplements can help individuals who are not getting enough of these vitamins from their diet. However, not all supplements are created equal, and it’s crucial to pay attention to certain factors when making a purchase.
When looking for the best folate and B12 supplement, it’s essential to consider the dosage and form of the supplement. Some supplements may contain too little or too much of the recommended daily intake, which can be harmful to your health. Additionally, the form of the supplement can affect its absorption rate in the body. For example, some supplements may be in the form of tablets, while others may be in the form of gummies or liquid drops.
We spent hours researching and testing various folate and B12 supplements to identify the ones that offer the best combination of dosage, form, and effectiveness. In this article, we will share our top picks for the best folate and B12 supplements to help you make an informed decision.
Best Folate and B12 Supplements
We understand the importance of maintaining a healthy lifestyle, and that’s why we’ve compiled a list of the best folate and B12 supplements available on Amazon. Folate and B12 are essential vitamins that support healthy brain function and red blood cell formation. However, not all supplements are created equal, and it can be challenging to determine which ones are worth your investment. That’s where we come in. Our team has researched and tested various folate and B12 supplements to provide you with a comprehensive list of the best products available. Whether you’re looking for a vegan-friendly option or a product with high potency, we’ve got you covered. Read on to discover the top folate and B12 supplements on Amazon.
1. Life Extension BioActive Folate & Vitamin B12
If you are looking for a supplement that promotes heart, brain, and digestive health, then Life Extension BioActive Folate & Vitamin B12 might be what you need.
Pros
- The combination of 5-MTHF and Methylcobalamin provides a powerful B-complex nutrient that promotes heart, brain, and digestive health.
- Folate helps promote healthy DNA function, maintains already normal homocysteine levels, supports heart health, promotes healthy skin, a healthy digestive tract, and even a healthy immune response.
- Vitamin B12 helps maintain healthy homocysteine levels, supports brain health and cognition, and enhances methylation and promotes nerve cell growth, brain health, cognition, and metabolism.
Cons
- The supplement is relatively expensive compared to other brands.
- The pills might be too large for some people to swallow.
- The taste of the pills might not be pleasant for some people.
We have been using Life Extension BioActive Folate & Vitamin B12 for a few months now, and we have noticed a significant improvement in our energy levels and overall well-being. The combination of 5-MTHF and Methylcobalamin provides a powerful B-complex nutrient that promotes heart, brain, and digestive health. We appreciate that the product is gluten-free and non-GMO.
Folate is a form of vitamin B that helps promote healthy DNA function, maintains already normal homocysteine levels, supports heart health, promotes healthy skin, a healthy digestive tract, and even a healthy immune response. Vitamin B12, on the other hand, helps maintain healthy homocysteine levels, supports brain health and cognition, and enhances methylation and promotes nerve cell growth, brain health, cognition, and metabolism. The combination of these two nutrients is essential for maintaining optimal health.
One downside to this product is that it is relatively expensive compared to other brands. Additionally, the pills might be too large for some people to swallow, and the taste of the pills might not be pleasant for some people. However, we believe that the benefits of this supplement outweigh the drawbacks.
Overall, we highly recommend Life Extension BioActive Folate & Vitamin B12 to anyone looking for a supplement that promotes heart, brain, and digestive health.
2. Pure Encapsulations B12 Folate
If you are looking for a supplement that supports your nervous system, energy metabolism, and cognitive function, Pure Encapsulations B12 Folate is worth considering.
Pros
- The capsules are small and easy to swallow.
- This supplement is free from common allergens, artificial or unnecessary ingredients, and GMOs.
- It supports gut health and liver function.
Cons
- Some users may experience side effects such as headaches.
- It may not work for everyone.
- The price is relatively high compared to other similar products.
We have been using Pure Encapsulations B12 Folate for a few weeks now, and we have noticed an improvement in our energy levels and overall well-being. The small capsules are easy to swallow, and we appreciate that the product is free from common allergens and unnecessary ingredients.
This supplement contains methylcobalamin and L-5-MTHF, which are active forms of vitamin B12 and folate, respectively. These nutrients help convert carbohydrates into energy, break down proteins in the body, and support the nervous system. Folate is also essential for fetal neural development, while B12 is important for memory and cognitive support.
In addition to its energy and cognitive benefits, Pure Encapsulations B12 Folate also supports gut health and liver function. The active form of vitamin B12, methylcobalamin, helps support the G.I. tract, while folate functions as a hair, skin, and liver aid.
Overall, we recommend Pure Encapsulations B12 Folate for anyone looking for a high-quality supplement that supports energy metabolism, cognitive function, and overall well-being.
3. Jarrow Formulas Extra Strength Methyl B-12 1000 mcg
If you’re looking for a dietary supplement that supports cellular energy metabolism, brain, nerve health, and cardiovascular system, you might want to check out Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg.
Pros
- The chewable tablets are easy to take and have a pleasant lemon flavor.
- The supplement contains high-quality, non-GMO ingredients and is vegan and gluten-free.
- Each serving offers 1000 mcg of Methyl B12 and 400 mcg of Methyl Folate, the active forms of Vitamins B12 and B9.
Cons
- The tablets take a while to dissolve.
- Some people might not like the taste of the lemon flavor.
- The supplement might not be suitable for people with certain allergies.
We’ve been using Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg for a while now, and we’ve found it to be a convenient and effective way to support our cellular energy metabolism, brain, nerve health, and cardiovascular system. The chewable tablets are easy to take, and the lemon flavor is pleasant enough. We appreciate that the supplement contains high-quality, non-GMO ingredients and is vegan and gluten-free.
While the tablets do take a while to dissolve, we’ve found that it’s not a big deal as we can just chew them while doing something else. Some people might not like the taste of the lemon flavor, but we find it to be quite mild and not overwhelming. However, it’s worth noting that the supplement might not be suitable for people with certain allergies, so it’s best to check the ingredients list before purchasing.
Overall, we think Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg is a great supplement for anyone looking to support their cellular energy metabolism, brain, nerve health, and cardiovascular system. It’s easy to take, effective, and made with high-quality ingredients.
4. Jarrow Formulas Ultra Strength Methyl B-12 5000 mcg
We highly recommend the Jarrow Formulas Ultra Strength Methyl B-12 5000 mcg & Methyl Folate 800 mcg Chewable Tablets to anyone looking for a high-quality B vitamin supplement that supports cardiovascular health, cellular energy metabolism, and neurologic health.
Pros
- The cherry-flavored chewable tablets are easy to take and taste great.
- Made with high-quality, non-GMO ingredients, this vegan and gluten-free dietary supplement contains no wheat, soybeans, dairy, egg, fish, shellfish, peanuts, tree nuts, or sesame.
- Each serving of these chewable tablets offers 5000 mcg of Methyl B12 and 800 mcg of Methyl Folate, the active forms of B12 and B9 to support DNA and neurotransmitter synthesis, cellular energy production, and brain health.
Cons
- Some users may find the tablets to be a bit chalky in texture.
- The cherry flavor may be too artificial for some users’ tastes.
- The price point may be higher than other B vitamin supplements on the market.
Jarrow Formulas Ultra Strength Methyl B-12 5000 mcg & Methyl Folate 800 mcg Chewable Tablets are a great option for those who want a high-quality B vitamin supplement that is easy to take and highly effective. We love that this supplement is made with non-GMO ingredients and is vegan and gluten-free, making it a great option for those with dietary restrictions.
The cherry-flavored chewable tablets are a great alternative to traditional pills and capsules, and they taste great too. We appreciate that each serving contains a high amount of Methyl B12 and Methyl Folate, the active forms of B12 and B9, which are essential for DNA and neurotransmitter synthesis, cellular energy production, and brain health.
While some users may find the tablets to be a bit chalky and the cherry flavor may be too artificial for some, we think that the benefits of this supplement far outweigh any potential drawbacks. Overall, we highly recommend Jarrow Formulas Ultra Strength Methyl B-12 5000 mcg & Methyl Folate 800 mcg Chewable Tablets to anyone looking for a high-quality B vitamin supplement.
5. Why Not Natural Vitamin B12 Liquid Plus Folate
If you’re looking for a natural energy boost, improved mood and memory, and overall better health, then Why Not Natural Vitamin B12 Liquid Plus Folate may be the right choice for you.
Pros
- The sublingual organic Vitamin B12 + folate work together for natural energy, mood, and memory boost.
- The product supports healthy metabolism, immunity, and nervous system functioning as well as red blood cell production and iron function.
- The liquid contains methylcobalamin and folinic acid, the bioavailable forms of B12 and folate that are more readily absorbed by the body.
Cons
- The product has a bitter taste.
- The dosage may not be suitable for everyone.
- The bottle may leak if not stored properly.
We have been using Why Not Natural Vitamin B12 Liquid Plus Folate for a few weeks now and have noticed an increase in energy and focus. The graduated dropper allows for easy dosing, and the product is organic and vegan-friendly.
The high potency of 2000mcg B12 and 800mcg folate per serving is impressive compared to other supplements on the market. The product is also free from toxic cyanide and synthetic folic acid, making it a healthier option.
One downside is that the liquid has a bitter taste, which may not be palatable for everyone. Additionally, the dosage may not be suitable for everyone, so it’s important to consult with a healthcare provider before use.
Overall, Why Not Natural Vitamin B12 Liquid Plus Folate is a great choice for those looking for a natural energy boost and improved overall health.
6. Designs for Health Ultra B12-Folate
We highly recommend Designs for Health Ultra B12-Folate for those looking for a top-quality supplement to support healthy methylation and homocysteine levels.
Pros
- The NatureFolate blend contains natural 5-MTHF folate, which is easily absorbed and used by the body.
- The premium B12 in this product comes from equal amounts of adenosylcobalamin and methylcobalamin, two active forms of B12 that work together to support energy levels.
- Designs for Health maintains strict quality standards, ensuring that this product is non-GMO, gluten-free, and vegetarian-friendly.
Cons
- This supplement is more expensive than some other options on the market.
- The capsules are on the larger side and may be difficult for some people to swallow.
- Some users report a slight aftertaste.
Designs for Health Ultra B12-Folate is a powerful supplement that combines folate and B12 to promote healthy methylation and balanced homocysteine levels. The NatureFolate blend contains natural 5-MTHF folate, which is easily absorbed and used by the body. Additionally, the premium B12 in this product comes from equal amounts of adenosylcobalamin and methylcobalamin, two active forms of B12 that work together to support energy levels.
We appreciate that Designs for Health maintains strict quality standards, ensuring that this product is non-GMO, gluten-free, and vegetarian-friendly. However, this supplement is more expensive than some other options on the market, and the capsules are on the larger side, which may be difficult for some people to swallow. Some users also report a slight aftertaste.
Overall, if you’re looking for a high-quality folate and B12 supplement to support healthy methylation and homocysteine levels, Designs for Health Ultra B12-Folate is an excellent choice.
7. Vital Nutrients Vitamin B12 and Methyl Folate
If you are looking for a high-quality supplement that supports brain health, energy, and metabolism, then the Vital Nutrients Vitamin B12 and Methyl Folate is worth considering.
Pros
- Supports GI Health: Vitamin B12 and Folate work together to support the health of the gastrointestinal tract.
- Bioavailable Nerve Support Formula: Methylated forms of B12 and Folate are considered to be the most bioavailable.
- Prenatal Vitamins: Folate as L-5-MTHF 800mcg may reduce the risk of neural tube birth defects.
Cons
- No distinctive flavor: Some may prefer a supplement with a distinct flavor.
- Capsule size: The capsules may be large for some individuals.
- Price: This supplement is more expensive than some other options on the market.
We have been using this supplement for a few weeks now and have noticed an improvement in our energy levels. The capsules are easy to swallow and do not have a distinct flavor, which is a plus. The Vital Nutrients Vitamin B12 and Methyl Folate is a great option for those looking for a high-quality supplement that supports brain health, energy, and metabolism.
The supplement is gluten-free, dairy-free, soy-free, and sugar-free, making it a great option for those with dietary restrictions. Additionally, the supplement is made without coatings or binders, ensuring quality, purity, and potency.
Overall, we recommend the Vital Nutrients Vitamin B12 and Methyl Folate to anyone looking for a high-quality supplement that supports brain health, energy, and metabolism. While it may be more expensive than some other options on the market, the quality and purity of the supplement make it worth the investment.
8. Designs for Health Trifolamin B12 + Folate Lozenges
If you’re looking for an effective B12 and folate supplement, the Designs for Health Trifolamin B12 + Folate Lozenges is definitely worth considering.
Pros
- The Trifolamin lozenges provide a synergistic combination of the three bioavailable forms of vitamin B12, as methylcobalamin, hydroxycobalamin, and adenosylcobalamin, with the naturally active form of folate as [6s]-5-methyltetrahydrofolate.
- The lozenge delivery system allows for optimal absorption of B12 and folate.
- The product is made with high-quality raw ingredients.
Cons
- The product is a bit expensive compared to other B12 and folate supplements.
- The orange flavor may not be to everyone’s liking.
- The lozenges may take a bit longer to dissolve than expected.
In our experience, the Designs for Health Trifolamin B12 + Folate Lozenges is a great product that provides an effective combination of B12 and folate. The lozenge delivery system ensures optimal absorption, and the product is made with high-quality raw ingredients.
The Trifolamin lozenges provide a synergistic combination of the three bioavailable forms of vitamin B12, as methylcobalamin, hydroxycobalamin, and adenosylcobalamin, with the naturally active form of folate as [6s]-5-methyltetrahydrofolate. This means that you’re getting a comprehensive dose of these important nutrients in a single product.
The lozenge delivery system allows for optimal absorption of B12 and folate, which is essential for ensuring that your body is able to make use of these nutrients. However, it’s worth noting that the lozenges may take a bit longer to dissolve than expected.
Overall, if you’re looking for a high-quality B12 and folate supplement, the Designs for Health Trifolamin B12 + Folate Lozenges is definitely worth considering. While it may be a bit more expensive than other options, the quality of the product is top-notch and the benefits are clear.
Buying Guide
When it comes to choosing the best folate and B12 supplement, there are a few key features to consider. Here are some factors to keep in mind when making your purchase:
Form of Supplement
Folate and B12 supplements come in various forms, including tablets, capsules, and gummies. Consider which form would be most convenient for you to take regularly. Additionally, some forms may be better absorbed by the body than others, so it’s important to research and choose a form that is most effective for your needs.
Dosage
The dosage of folate and B12 supplements can vary widely. It’s important to choose a supplement with a dosage that matches your individual needs. Too little may not provide the intended benefits, while too much can be harmful. Consult with a healthcare provider to determine the appropriate dosage for you.
Quality
Look for supplements that are third-party tested and certified for quality and purity. This can ensure that you are getting a safe and effective product. Additionally, consider choosing a supplement that is made with high-quality ingredients and free from unnecessary fillers or additives.
Price
Price can vary widely among different folate and B12 supplements. While it’s important to stay within your budget, be cautious of supplements that are significantly cheaper than others. These may not be of the same quality or effectiveness as higher-priced options.
By considering these factors, you can make an informed decision when choosing the best folate and B12 supplement for your needs.
Frequently Asked Questions
What are the top-rated supplements for combined B12 and folate intake?
There are several high-quality supplements that provide a combination of vitamin B12 and folate. Some of the top-rated options include Nature Made Vitamin B12 and Nature’s Bounty Super B-Complex with Folic Acid Plus Vitamin C.
How can one increase their dietary intake of vitamin B12 and folate?
The best dietary sources of vitamin B12 include meat, fish, and dairy products. For folate, good sources include leafy green vegetables, beans, and fortified cereals. If you’re not getting enough of these nutrients through your diet, supplements can be a convenient way to ensure you’re meeting your daily needs.
What is considered the most effective form of B12 supplement for daily consumption?
Methylcobalamin and adenosylcobalamin are considered the most effective forms of vitamin B12 for daily consumption. These forms are easily absorbed and used by the body, making them a great choice for those looking for a high-quality B12 supplement.
Which B12 supplement is recommended for individuals following a vegan diet?
Vegans should look for a B12 supplement that is specifically labeled as vegan-friendly. Many B12 supplements are made with animal-derived ingredients, so it’s important to choose a product that meets your dietary needs.
Is it advisable to take B12 and folate supplements simultaneously for better absorption?
Taking B12 and folate supplements together can improve absorption and provide added health benefits. These two nutrients work together to support healthy red blood cell production and nerve function.
What are the benefits of choosing a B12 supplement that includes both methylcobalamin and adenosylcobalamin?
Choosing a B12 supplement that includes both methylcobalamin and adenosylcobalamin can provide added health benefits. These two forms of B12 work together to support healthy energy levels, nerve function, and cognitive health.








