Adrian Dix: Finding evidence for prescription drug reform at the movies

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      On Friday night, I went to see a big budget movie and found evidence in support of prescription drug reform. Love and Other Drugs, a new movie starring Jake Gyllenhaal and Anne Hathaway, is a bit of a mess: a few great performances, a love story that doesn’t quite work, and moving scenes depicting the impact of Parkinson’s disease. Into this stew, throw in bizarrely sexist portrayals of every woman other than Anne Hathaway’s character, plus an inane subplot involving the lead male’s brother, reminiscent of outtakes from a Zach Galifianakis film.

      The movie is not an artistic success—but it mostly held my attention. And that’s because of a biting portrayal of the pharmaceutical industry in the mid 1990s, when armies of sales reps blitzed the offices of family doctors—embodied by the gung-ho charm of Gyllenhaal’s character, a Pfizer rep in Ohio, battling his Eli Lilly competitor: at stake, Zoloft versus Prozac. He attends a pharma boot camp and learns how to sneak in references to “off-label” uses of prescription drugs (uses not approved by the FDA); most importantly, he learns on the job how best to get into doctors’ offices to drop off samples and offer less orthodox inducements to prescribe the company’s drug.

      While the competition between the firms is depicted as fierce (Gyllenhaal’s character is beaten up by a Lilly rep), the greater competition comes from less expensive generic drugs. The job of the representatives is clear—increase the number of prescriptions of the most expensive drugs by any means necessary.

      The victims of these drug-sale tactics appear in minor but poignant scenes—Anne Hathaway’s character, who suffers from Stage 1 Parkinson’s disease, organizes a busload of American seniors to drive up to Canada where they’ll be able to access needed and more affordable prescriptions available in a country with more public controls on drug pricing.

      Here in British Columbia, there are 600 to 700 “drug detailers”—representatives of pharmaceutical companies who promote prescription drugs to doctors and other health professionals. Estimates place about 6,000 such “drug detailers” in doctor’s offices across Canada.

      There are 10,000 physicians and 5,448 general practitioners in our province. According to the 2006 BCMA Prescription Drug Survey, “Two out three physicians report visits from drug company sales representatives at least once per month, 42% of GP visited several times per week.”

      The job of the “drug detailer” is just like in the movie—to promote a particular company’s product. Life does imitate art. In a recent edition of the Canadian Medical Association Journal, Dr. Aaron Tejani, co-coordinator of drug information for Fraser Health, describes meeting with a pharmaceutical representative who had promoted “off-label” use of the drug Aricept. The drug detailer worked for Pfizer.

      In order to combat big pharma’s ratio of rep to doctor transactions, I advocate academic detailing as a counter measure. In a consumer culture where “direct detailing” for merchandise is endemic, academic detailing stands out as an alternative. Here’s how it works: the government hires pharmacists to visit and provide doctors with unbiased information to counterbalance promotional materials delivered by the pharma reps. Much of that information is provided by the Therapeutics Initiative, an independent group at UBC whose role in drug reviews has been sidelined by just-resigned health minister Kevin Falcon. Along with the TI, the NDP government initiated B.C.’s first academic detailing program in the 1990s. Currently, there are nine academic detailing positions in all of the health authorities. I want to see the program substantially expanded, increasing its counterbalancing effect.

      According to the Health Council of Canada, “Academic Detailing is an effective strategy for influencing the practices of health professionals....The goal is not to promote a new drug but to educate physicians about the best way to prescribe for their patients.” Further, a report by the New England Journal of Medicine showed that for every dollar spent on academic detailing programs, more than two dollars are saved. Academic detailing improves health outcomes and saves money.

      Perhaps, we can plan a sequel to Love and Other Drugs where a feisty academic detailer, trained at UBC, fights Big Pharma by providing evidence-based information to doctors. Not a box office winner? Okay, then let’s make it happen in real life by doubling the number of academic detailers at work in B.C.

      Adrian Dix is the NDP health critic and the MLA for Vancouver-Kingsway.

      Comments

      9 Comments

      P

      Nov 30, 2010 at 8:27pm

      Gee he gets his facts from the movies. What next Jesse Ventura's conspiracy theories for information regarding vaccinations as a means of controlling human population. This is a health critic?

      glen p robbins

      Nov 30, 2010 at 8:39pm

      Very enjoyable read. The drug detailers are prolific in order to make sales, on this we agree. Your theory as I read it Adrian is that this method of interaction may promote sales but not necessarily an inclination toward prescribing drugs to patients that are correct for the patient. If this is the case - it is an indictment of the ethics of the medical profession or some in the profession. If is isn't - I would need it explained how it isn't. It may be true at least in part - but if it is - then we need to ask ourselves how this is so. Should future governments follow the Robbins formula of Civilian Oversight -- for the medical profession as well as police and lawyers?

      Also, I get the impression that if academic detailers are introduced by government-- then a corresponding drop in sales will occur. The push for sales as I understand it - is a consequence of the high front end costs for Pharmas to produce products with a short shelf life of proprietorial protection -- and accordingly if they can't recoup their dollars -- through the apparently emphatic sales propulsion -- high costs will likely result.

      How do we recognize the need for complete ethical excellence in the medical profession, the protection of consumers - and properly consider the impact of market drivers on consumer pocket books.

      I am certainly looking forward to your response.

      glen p

      RonS

      Nov 30, 2010 at 9:18pm

      Keep at it Adrian, these underhanded sales reps are the wedges big pharma and American Hospital Insurance companies are using to dismantle our health care system. Good work!

      poopnoodle

      Nov 30, 2010 at 9:38pm

      Damn recession
      Less free lunches from drug reps
      Wanna save money Dix, ban fee-for-service provision
      Hire more nurse practitioners

      plen r gobbins

      Nov 30, 2010 at 11:14pm

      "Should future governments follow the Robbins formula"

      Jebus could you get any more full of yourself? Future governments need to follow the Gobbins methods if humanity wants any hope at all.

      Robert Bethune

      Dec 1, 2010 at 5:35am

      Of course, there are some situations where there's no need for drug reps. If you have, for example, chronic myelogenous leukemia, there are no generic drugs, and the three that are out there all cost about twice as much than the average family earns in a year--or more.

      glen p robbins

      Dec 1, 2010 at 4:34pm

      Robbins formula on Civilian Oversight my babbling brother.

      welldoneson

      Dec 1, 2010 at 11:26pm

      Years ago, Dix posted a fake memo, with a fake date, stating that his fearless leader Glen Clark had no knowledge of some scam the NDP were pulling. Not only did Dix do that but he KNEW Clark did in fact have knowledge of the issue in question.

      Such a cheating liar should be nowhere near any political power.

      The very idea that ANYONE thinks Dix is quoteworthy seems positively idiotic. It's no surprise that he's still enough of a mucky-muck in the NDP that he's their health "critic". Shows how shallow their talent pool is.

      So much that comes from the NDP is just the usual anti-corporate small-m marxist boilerplate. Actually attempting to implement such nonsense is criminally irresponsible; yet, that is the NDP's act.
      Well, that and paying off the public sector unions, for the NDP are a putrid combination of "socialism" and "labor". The two are not the same, in fact the two are not even compatible, which is why there is so much turmoil in the NDP backroom. And it explains why they have creeps like Dix front and centre, providing red herrings to distract the voters from the grim reality of NDP tomfoolery.

      drugpreventioned

      Dec 25, 2010 at 11:33am

      The American Academy of Pediatrics Report states: A controlled medication was prescribed at 2.3 million visits by adolescents (aged 15–19 years) and at 7.8 million visits by young adults (aged
      20 –29 years) in 1994. That number increased to 5.7 million visits by adolescents and 18.6 million visits by young adults in 2007. A 58 % increase in 9 years.

      Also from the AAP report between 1997 and 2006, the sale of oxycodone increased by 732%, hydrocodone by 244%, and methadone by 1177%.

      Watch this 2.5 minute CBS investigative report about Pill Mills
      http://www.cbsnews.com/video/watch/?id=2872826n

      The AMA is responsible for addicting and killing thousands without accountability. When will we stop this legal drug dealing by the pharmaceutical corporations and the AMA?

      www.drugpreventioned.com